Doryx Delayed-Release Capsules

|Doryx Delayed-Release Capsules

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Doryx Delayed-Release Capsules

Generic Name: Doxycycline Delayed-Release Capsules (dox-ee-SYE-kleen)
Brand Name: Doryx

Doryx Delayed-Release Capsules is used for:

Treating certain bacterial infections. It may be used in combination with other medicines to treat acne or amoeba infections in the intestines. It may be used to prevent certain types of malaria in travellers who will be visiting malaria-infected areas for less than 4 months. It may also be used to prevent or slow the progression of anthrax after exposure.

Doryx Delayed-Release Capsules is a tetracycline antibiotic. It works by interfering with the growth of the bacteria.

Do NOT use Doryx Delayed-Release Capsules if:

  • you are allergic to any ingredient in Doryx Delayed-Release Capsules or any other tetracycline antibiotic (eg, minocycline)
  • you are currently taking acitretin, methoxyflurane, isotretinoin, or a penicillin (eg, amoxicillin)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Doryx Delayed-Release Capsules:

Some medical conditions may interact with Doryx Delayed-Release Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diarrhea, a stomach infection, or porphyria

Some MEDICINES MAY INTERACT with Doryx Delayed-Release Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), or iron because they may decrease Doryx Delayed-Release Capsules"s effectiveness
  • Acitretin, anticoagulants (eg, warfarin), isotretinoin, methotrexate, or methoxyflurane because their side effects may be increased by Doryx Delayed-Release Capsules
  • Birth control pills or penicillins (eg, amoxicillin) because their effectiveness may be decreased by Doryx Delayed-Release Capsules

This may not be a complete list of all interactions that may occur. Ask your health care provider if Doryx Delayed-Release Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Doryx Delayed-Release Capsules:

Use Doryx Delayed-Release Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Doryx Delayed-Release Capsules by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Swallow Doryx Delayed-Release Capsules whole. Do not break, crush, or chew before swallowing. If you cannot swallow the capsule whole, you may open it and sprinkle the contents over a spoonful of applesauce. Mix the medicine with the applesauce and swallow the mixture right away, followed by a glass of water. Do not crush or chew the medicine before swallowing. Do not store the mixture for future use.
  • Take Doryx Delayed-Release Capsules with a full glass of water (8 oz/240 mL).
  • Do not take an antacid that has aluminum, magnesium, or calcium in it; sodium bicarbonate; or bismuth salts (eg, bismuth subsalicylate) within 2 hours of taking Doryx Delayed-Release Capsules.
  • To clear up your infection completely, take Doryx Delayed-Release Capsules for the full course of treatment. Keep taking it even if you feel better in a few days.
  • If you miss a dose of Doryx Delayed-Release Capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Doryx Delayed-Release Capsules.

Important safety information:

  • Be sure to use Doryx Delayed-Release Capsules for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Doryx Delayed-Release Capsules only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Long-term or repeated use of Doryx Delayed-Release Capsules may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • If you are taking Doryx Delayed-Release Capsules to prevent malaria, please note that no malaria medicine, including Doryx Delayed-Release Capsules, guarantees protection against malaria. Stay in well-screened areas, use mosquito nets, cover the body with clothing, and use insect repellant to avoid being bitten by mosquitoes.
  • Doryx Delayed-Release Capsules may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Doryx Delayed-Release Capsules. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Diabetes patients - Doryx Delayed-Release Capsules may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Lab tests may be performed while you use Doryx Delayed-Release Capsules. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Doryx Delayed-Release Capsules should not be used in CHILDREN younger than 8 years old; safety and effectiveness in these children have not been confirmed. Use of Doryx Delayed-Release Capsules during tooth development may leave a permanent yellow-gray-brown tooth discoloration.
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Doryx Delayed-Release Capsules. To prevent pregnancy, use an extra form of birth control (eg, condoms).
  • PREGNANCY and BREAST-FEEDING: Doryx Delayed-Release Capsules has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Doryx Delayed-Release Capsules while you are pregnant. Doryx Delayed-Release Capsules is found in breast milk. Do not breast-feed while taking Doryx Delayed-Release Capsules.

Possible side effects of Doryx Delayed-Release Capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; loss of appetite; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; headache; prolonged or severe diarrhea; severe skin reaction to the sun; stomach pain; vaginal irritation or itching.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately.

Proper storage of Doryx Delayed-Release Capsules:

Store Doryx Delayed-Release Capsules at or below 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Doryx Delayed-Release Capsules out of the reach of children and away from pets.

General information:

  • If you have any questions about Doryx Delayed-Release Capsules, please talk with your doctor, pharmacist, or other health care provider.
  • Doryx Delayed-Release Capsules is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Doryx Delayed-Release Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition
Copyright © 2006 Wolters Kluwer Health, Inc.


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