Pyridostigmine Syrup

|Pyridostigmine Syrup

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Pyridostigmine Syrup

Generic Name: Pyridostigmine Syrup (peer-id-oh-STIG-meen)
Brand Name: Mestinon

Pyridostigmine Syrup is used for:

Treating myasthenia gravis. It may also be used for other conditions as determined by your doctor.

Pyridostigmine Syrup is a cholinesterase inhibitor. It works by improving nerve impulses in muscles so that the muscles are better able to work.

Do NOT use Pyridostigmine Syrup if:

  • you are allergic to any ingredient in Pyridostigmine Syrup
  • you are taking quinine or quinidine
  • you have a stomach, intestinal, or urinary blockage

Contact your doctor or health care provider right away if any of these apply to you.

Before using Pyridostigmine Syrup:

Some medical conditions may interact with Pyridostigmine Syrup. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart problems (eg, heart block, slow heartbeat), a urinary tract infection, asthma, or kidney problems

Some MEDICINES MAY INTERACT with Pyridostigmine Syrup. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Quinine or quinidine because effectiveness of Pyridostigmine Syrup may be decreased
  • Succinylcholine because actions and side effects may be increased by Pyridostigmine Syrup

This may not be a complete list of all interactions that may occur. Ask your health care provider if Pyridostigmine Syrup may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Pyridostigmine Syrup:

Use Pyridostigmine Syrup as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Pyridostigmine Syrup may be taken with or without food. Take with food if it upsets your stomach.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of Pyridostigmine Syrup, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Pyridostigmine Syrup.

Important safety information:

  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Pyridostigmine Syrup.
  • Use Pyridostigmine Syrup with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Pyridostigmine Syrup, discuss with your doctor the benefits and risks of using Pyridostigmine Syrup during pregnancy. Pyridostigmine Syrup is excreted in breast milk. If you are or will be breast-feeding while you are using Pyridostigmine Syrup, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Pyridostigmine Syrup:

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); diarrhea; fainting; increased production of saliva; increased sweating; muscle weakness; nausea; small pupils; stomach cramps; trouble breathing; vision changes; vomiting; weakness.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately. Symptoms may include diarrhea; fainting; increased production of saliva; increased sweating; muscle weakness; nausea; small pupils; stomach cramps; trouble breathing; vision changes; vomiting; weakness.

Proper storage of Pyridostigmine Syrup:

Store Pyridostigmine Syrup between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Pyridostigmine Syrup out of the reach of children and away from pets.

General information:

  • If you have any questions about Pyridostigmine Syrup, please talk with your doctor, pharmacist, or other health care provider.
  • Pyridostigmine Syrup is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Pyridostigmine Syrup. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: November 1, 2006
Database Edition
Copyright © 2006 Wolters Kluwer Health, Inc.


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