Rabies Immune Globulin, Human

Drugspedia.net

|Rabies Immune Globulin, Human

Drugs search, click the first letter of a drug name: | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | 1 | 2 | 3 | 4 | 5 | 6 | 8 | 9

   


Rabies Immune Globulin, Human

( RIG ) Pronouncation: (RAY-beez ih-MYOON GLAB-byoolin)
Class: Immune globulin

Trade Names:
BayRab
- Injection 150 units/mL

Trade Names:
Imogam Rabies-HT
- Injection 150 units/mL

Mechanism of Action

Pharmacology

Directly neutralizes rabies virus.

Pharmacokinetics

Absorption

Absorbed slowly (IM). T max is 2 to 13 days.

Distribution

Distribution into milk and across placenta likely due to passage of other immunoglobulins.

Elimination

The t ½ serum is about 24 days.

Indications and Usage

Passive, transient postexposure prevention of rabies infection in susceptible individuals.

Contraindications

Repeated doses once vaccine treatment has been initiated. Rabies immune globulin (RIG) may theoretically be contraindicated in people who have had life-threatening reactions to human IgG antibody products or any RIG components. Previous complete immunization with rabies vaccine and presence of adequate antibody titer.

Dosage and Administration

Adults and children

IM 20 units/kg (0.133 mL/kg) as soon as possible after exposure, preferably with first dose of rabies vaccine, but can be administered through the seventh day after the first dose of vaccine is given.

General Advice

  • For IM administration only. Not for intradermal, subcutaneous, IV, intra-arterial, or oral administration.
  • Can be administered in conjunction with rabies vaccine if not combined in the same syringe or administered in the same site.
  • Infiltrate as much immune globulin as possible around the wound if anatomically feasible. Administer remaining immune globulin IM in the upper, outer quadrant of the gluteal muscle, or the deltoid muscle.
  • Administer 2 injections in gluteal region if volume is greater than 5 mL.
  • Inspect solution visually before administration. Do not administer if solution is cloudy, discolored, or contains particulate matter.
  • Discard any unused product. Vials are for single-use only. Do not save medication for future use.

Storage/Stability

Store vials in refrigerator (36° to 46°F). Protect from freezing. Do not use if solution has been frozen.

Drug Interactions

Measles, mumps, polio, or rubella live vaccines

Other antibodies in RIG preparation may interfere with response to these live vaccines. Do not give live vaccines within 3 mo after RIG.

Laboratory Test Interactions

None well documented.

Adverse Reactions

Dermatologic

Urticaria; skin rash.

Genitourinary

Nephrotic syndrome.

Miscellaneous

Local tenderness, pain, soreness, or stiffness of the muscles at injection site; low-grade fever; angioedema; sensitization to repeated injections; anaphylactic shock.

Precautions

Pregnancy

Category C .

Lactation

Unknown.

Hypersensitivity to human immunoglobulins

Give drug with caution.

Bloodborne viral transmission

Because RIG is made from human plasma, there is a risk of transmitting infectious agents (eg, viruses).

Patient Information

  • Explain name, actions, and potential side effects of the treatment regimen. Review the treatment regimen including dosing schedule, duration of treatment, and monitoring that will be required.
  • Review benefits of therapy and risks, including potential to transmit disease and unknown infectious agents.
  • Advise patient, family, or caregiver that medication will be prepared and administered by a health care provider in a health care setting and that medication will not be administered at home.
  • Advise patient or caregiver that most common side effects are soreness at injection site and fever. Advise patient or caregiver to use nonaspirin containing OTC analgesics (eg, acetaminophen, ibuprofen) for fever, or pain or discomfort at injection site.
  • If appropriate, teach patient or caregiver wound care, and signs of infection that should be reported to health care provider.
  • Advise women to notify health care provider if pregnant, planning to become pregnant, or breastfeeding.
  • Instruct patient not to take any prescription or OTC medications, herbal preparations, or dietary supplements unless advised by health care provider.
  • Advise patient or caregiver that follow-up visits and lab tests may be required to monitor response to therapy and to keep appointments.




1

eabies immune globulin, human, dabies immune globulin, human, fabies immune globulin, human, tabies immune globulin, human, 5abies immune globulin, human, 4abies immune globulin, human, rzbies immune globulin, human, rsbies immune globulin, human, rwbies immune globulin, human, rqbies immune globulin, human, ravies immune globulin, human, ranies immune globulin, human, rahies immune globulin, human, ragies immune globulin, human, rabues immune globulin, human, rabjes immune globulin, human, rabkes immune globulin, human, raboes immune globulin, human, rab9es immune globulin, human, rab8es immune globulin, human, rabiws immune globulin, human, rabiss immune globulin, human, rabids immune globulin, human, rabirs immune globulin, human, rabi4s immune globulin, human, rabi3s immune globulin, human, rabiea immune globulin, human, rabiez immune globulin, human, rabiex immune globulin, human, rabied immune globulin, human, rabiee immune globulin, human, rabiew immune globulin, human, rabies ummune globulin, human, rabies jmmune globulin, human, rabies kmmune globulin, human, rabies ommune globulin, human, rabies 9mmune globulin, human, rabies 8mmune globulin, human, rabies inmune globulin, human, rabies ikmune globulin, human, rabies ijmune globulin, human, rabies imnune globulin, human, rabies imkune globulin, human, rabies imjune globulin, human, rabies immyne globulin, human, rabies immhne globulin, human, rabies immjne globulin, human, rabies immine globulin, human, rabies imm8ne globulin, human, rabies imm7ne globulin, human, rabies immube globulin, human, rabies immume globulin, human, rabies immuje globulin, human, rabies immuhe globulin, human, rabies immunw globulin, human, rabies immuns globulin, human, rabies immund globulin, human, rabies immunr globulin, human, rabies immun4 globulin, human, rabies immun3 globulin, human, rabies immune flobulin, human, rabies immune vlobulin, human, rabies immune blobulin, human, rabies immune hlobulin, human, rabies immune ylobulin, human, rabies immune tlobulin, human, rabies immune gkobulin, human, rabies immune gpobulin, human, rabies immune goobulin, human, rabies immune glibulin, human, rabies immune glkbulin, human, rabies immune gllbulin, human, rabies immune glpbulin, human, rabies immune gl0bulin, human, rabies immune gl9bulin, human, rabies immune glovulin, human, rabies immune glonulin, human, rabies immune glohulin, human, rabies immune glogulin, human, rabies immune globylin, human, rabies immune globhlin, human, rabies immune globjlin, human, rabies immune globilin, human, rabies immune glob8lin, human, rabies immune glob7lin, human, rabies immune globukin, human, rabies immune globupin, human, rabies immune globuoin, human, rabies immune globulun, human, rabies immune globuljn, human, rabies immune globulkn, human, rabies immune globulon, human, rabies immune globul9n, human, rabies immune globul8n, human, rabies immune globulib, human, rabies immune globulim, human, rabies immune globulij, human, rabies immune globulih, human, rabies immune globulin, guman, rabies immune globulin, buman, rabies immune globulin, numan, rabies immune globulin, juman, rabies immune globulin, uuman, rabies immune globulin, yuman, rabies immune globulin, hyman, rabies immune globulin, hhman, rabies immune globulin, hjman, rabies immune globulin, himan, rabies immune globulin, h8man, rabies immune globulin, h7man, rabies immune globulin, hunan, rabies immune globulin, hukan, rabies immune globulin, hujan, rabies immune globulin, humzn, rabies immune globulin, humsn, rabies immune globulin, humwn, rabies immune globulin, humqn, rabies immune globulin, humab, rabies immune globulin, humam, rabies immune globulin, humaj, rabies immune globulin, humah, abies immune globulin, human, rbies immune globulin, human, raies immune globulin, human, rabes immune globulin, human, rabis immune globulin, human, rabie immune globulin, human, rabiesimmune globulin, human, rabies mmune globulin, human, rabies imune globulin, human, rabies imune globulin, human, rabies immne globulin, human, rabies immue globulin, human, rabies immun globulin, human, rabies immuneglobulin, human, rabies immune lobulin, human, rabies immune gobulin, human, rabies immune glbulin, human, rabies immune gloulin, human, rabies immune globlin, human, rabies immune globuin, human, rabies immune globuln, human, rabies immune globuli, human, rabies immune globulin human, rabies immune globulin,human, rabies immune globulin, uman, rabies immune globulin, hman, rabies immune globulin, huan, rabies immune globulin, humn, rabies immune globulin, huma, arbies immune globulin, human, rbaies immune globulin, human, raibes immune globulin, human, rabeis immune globulin, human, rabise immune globulin, human, rabie simmune globulin, human, rabiesi mmune globulin, human, rabies mimune globulin, human, rabies imumne globulin, human, rabies immnue globulin, human, rabies immuen globulin, human, rabies immun eglobulin, human, rabies immuneg lobulin, human, rabies immune lgobulin, human, rabies immune golbulin, human, rabies immune glboulin, human, rabies immune gloublin, human, rabies immune globluin, human, rabies immune globuiln, human, rabies immune globulni, human, rabies immune globuli,n human, rabies immune globulin ,human, rabies immune globulin,h uman, rabies immune globulin, uhman, rabies immune globulin, hmuan, rabies immune globulin, huamn, rabies immune globulin, humna, rrabies immune globulin, human, raabies immune globulin, human, rabbies immune globulin, human, rabiies immune globulin, human, rabiees immune globulin, human, rabiess immune globulin, human, rabies immune globulin, human, rabies iimmune globulin, human, rabies immmune globulin, human, rabies immmune globulin, human, rabies immuune globulin, human, rabies immunne globulin, human, rabies immunee globulin, human, rabies immune globulin, human, rabies immune gglobulin, human, rabies immune gllobulin, human, rabies immune gloobulin, human, rabies immune globbulin, human, rabies immune globuulin, human, rabies immune globullin, human, rabies immune globuliin, human, rabies immune globulinn, human, rabies immune globulin,, human, rabies immune globulin, human, rabies immune globulin, hhuman, rabies immune globulin, huuman, rabies immune globulin, humman, rabies immune globulin, humaan, rabies immune globulin, humann, etc.

USA hospitals | Natural mosquito repellent | New 401k contribution limits | PMS | Blue waffles disease | Keratosis pilaris on face tretment


© Copyright by Drugspedia.net 2006-2007. All rights reserved