Toradol

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Toradol, Toradol IM, Toradol IV/IM, |Toradol

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Toradol

Generic Name: ketorolac (kee TORE oh lack)
Brand Names: Toradol, Toradol IM, Toradol IV/IM

What is ketorolac?

Ketorolac is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Ketorolac works by reducing chemicals that cause inflammation and pain in the body.

Ketorolac is used to treat moderate pain.

Ketorolac may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about ketorolac?

Ketorolac is intended for short-term use only, usually up to 5 days. Do not use ketorolac for longer or in larger doses than is prescribed by your doctor. Larger doses or longer treatment may not provide increased pain relief, and may increase the risk of serious side effects.

Your healthcare provider may recommend taking oral ketorolac with food or milk to lessen stomach upset. Follow your doctor"s instructions. If you drink more than three alcoholic beverages a day, ketorolac may increase the risk of stomach bleeding. Talk to your doctor before taking ketorolac if you drink more than 3 alcoholic beverages a day.

What should I discuss with my healthcare provider before taking ketorolac?

Do not take ketorolac without first talking to your doctor if you
  • have an allergy to aspirin or to any other NSAIDs such as ibuprofen (Advil, Motrin, Nuprin, others), naproxen (Naprosyn, Aleve, Anaprox, others), ketoprofen (Orudis, Orudis KT, Oruvail), indomethacin (Indocin), oxaprozin (Daypro), nabumetone (Relafen), and others;

  • have an ulcer or bleeding in the stomach;

  • drink more than three alcoholic beverages a day;

  • have liver or kidney disease;
  • have bleeding or blood clotting problems;

  • have congestive heart failure;

  • have fluid retention;

  • have heart disease; or

  • are taking probenecid (Benemid).

You may not be able to take ketorolac, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Ketorolac is in the FDA pregnancy category C. This means that it is not known whether ketorolac will be harmful to an unborn baby. However, ketorolac should not be taken during the last 3 months of pregnancy (the third trimester) because a similar drug is known to affect the baby"s heart. Do not take ketorolac without first talking to your doctor if you are pregnant or could become pregnant during treatment. Ketorolac passes into breast milk and may affect a nursing baby. Do not take this medicine without first talking to your doctor if you are breast-feeding a baby. If you are over 65 years of age, you may be more likely to experience side effects from ketorolac. Your doctor may prescribe a lower dose of the medication.

How should I take ketorolac?

Take ketorolac exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Ketorolac is available as pills for administration by mouth and as a solution for injection into the muscle (intramuscular) or vein (intravenous). If you are using injectable ketorolac at home, your healthcare provider will give you detailed instructions regarding preparation, administration, and storage of the medication.

Take each oral dose with a full glass of water. Your healthcare provider may recommend taking oral ketorolac with food or milk to lessen stomach upset. Follow your doctor"s instructions.

Ketorolac is intended for short-term use only, usually up to 5 days. Do not use ketorolac for longer or in larger doses than is prescribed by your doctor. Larger doses or longer treatment may not provide increased pain relief, and may increase the risk of serious side effects.

Do not share this medication with others. Keep it out of the reach of children. Throw away any unused medication. Ketorolac may be harmful if used by someone for whom it was not prescribed.

Store ketorolac at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a ketorolac overdose may include nausea, vomiting, stomach pain, drowsiness, lethargy, increased blood pressure, kidney problems, and difficulty breathing.

What should I avoid while taking ketorolac?

If you drink more than three alcoholic beverages a day, ketorolac may increase the risk of stomach bleeding. Talk to your doctor before taking ketorolac if you drink more than 3 alcoholic beverages a day.

Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or NSAIDs (such as ibuprofen, naproxen, ketoprofen, and others) which may interact with ketorolac. Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.

Ketorolac side effects

If you experience any of the following serious side effects, stop taking ketorolac and seek medical treatment or contact your doctor immediately:
  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

  • rapid weight gain (fluid retention);

  • abdominal pain or cramping, heartburn, or indigestion;

  • black, bloody, or tarry stools;

  • blood in urine or vomit;

  • side or back pain, or decreased urine production; or

  • jaundice (yellowing of the skin or eyes).

Other, less serious side effects may be more likely to occur. Continue to take ketorolac and talk to your doctor if you experience

  • dizziness or headache;

  • nausea or diarrhea;

  • fatigue; or

  • itching or rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect ketorolac?

Do not take ketorolac without first talking to your doctor if you are taking probenecid (Benemid). Probenecid may increase the amount of ketorolac in the body, which could be dangerous.

Before taking ketorolac, talk to your doctor if you are taking any of the following drugs:

  • a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, others), ketoprofen (Orudis, Orudis KT, Oruvail), naproxen (Naprosyn, Aleve, Anaprox); diclofenac (Voltaren, Cataflam), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), or tolmetin (Tolectin);
  • celecoxib (Celebrex), rofecoxib (Vioxx), or valdecoxib (Bextra);

  • aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), choline salicylate, or magnesium salicylate;

  • a diuretic (water pill) such as hydrochlorothiazide (HCTZ, Hydrodiuril, others), chlorothiazide (Diuril, others), chlorthalidone (Thalitone, Hygroton), bumetanide (Bumex), ethacrynic acid (Edecrin), furosemide (Lasix), spironolactone (Aldactone), or amiloride (Midamor);

  • an angiotensin-converting-enzyme inhibitor (ACE inhibitor) such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), quinapril (Accupril), ramipril (Altace), and others;

  • an anticoagulant such as warfarin (Coumadin);

  • a seizure medicine such as carbamazepine (Tegretol) or phenytoin (Dilantin, Phenytek);

  • methotrexate (Rheumatrex, Trexall);

  • lithium (Eskalith, Lithobid, others); or

  • cyclosporine (Sandimmune, Neoral).

You may not be able to take ketorolac, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with ketorolac. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

  • Your pharmacist has additional information about ketorolac written for health professionals that you may read.

What does my medication look like?

Ketorolac is available with a prescription under the brand name Toradol. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Toradol 10 mg--round, white, film-coated tablets

  • Toradol 15 mg-solution for injection

  • Toradol 30 mg-solution for injection

  • Toradol 60 mg-solution for injection

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ("Multum") is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum"s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum"s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 6.03. Revision Date: 8/23/04 4:49:56 PM.




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