Eldepryl, Zelapar, |Zelapar
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Generic Name: selegiline (oral) (se LE ji leen)
What is selegiline?
Selegiline prevents the breakdown of a chemical in your brain called dopamine (DO pa meen). Low levels of this chemical are associated with Parkinson"s disease.
Selegiline is used together with other medicines to treat symptoms of Parkinson"s disease.
Selegiline may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about selegiline?
There are many other medicines that can cause serious medical problems if you take them together with selegiline. Tell your doctor about all other prescription and over-the-counter medications you use, including vitamins, minerals, and herbal products.While taking selegiline, do not drink alcohol or eat foods that are high in tyramine, listed in the "What should I avoid while using selegiline?" section of this leaflet. Eating tyramine while you are using selegiline can raise your blood pressure to dangerous levels and cause life-threatening symptoms.
You should become very familiar with the list of foods to avoid while you are using selegiline.Do not stop taking selegiline suddenly or you may have harmful side effects. Keep taking the medicine as prescribed. Talk with your doctor before stopping the medication.
What should I discuss with my healthcare provider before using selegiline?Do not use this medication if you are allergic to selegiline, or if you have used any of the following drugs within the past 14 days:
After you stop taking selegiline, you must wait at least 14 days before taking any of the medications listed above.
Before using this medicine, tell your doctor if you have kidney disease, liver disease, heart disease, high or low blood pressure, or a seizure disorder. If you have any of these conditions, you may not be able to use selegiline, or you may need a dosage adjustment or special tests during treatment.FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether selegiline passes into breast milk or if it could harm a nursing baby. Do not take selegiline without telling your doctor if you are breast-feeding a baby.
The selegiline disintegrating tablets may contain phenylalanine. Talk to your doctor before using this form of selegiline if you have phenylketonuria (PKU).
How should I take selegiline?
Take selegiline exactly as it was prescribed for you. Do not take the medication in larger amounts or for longer than recommended by your doctor. Larger doses will not have any greater effect, but serious side effects could result. Follow the directions on your prescription label.While you are using selegiline and for 14 days after you stop, you must not eat foods listed in the "What should I avoid while using selegiline?" section of this leaflet. Eating these foods while you are using selegiline can raise your blood pressure to dangerous levels.
Foods that you MAY eat include:
To take selegiline orally disintegrating tablets (Zelapar):
Parkinson"s disease is often treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. When you start taking selegiline, your doses of the other medications may need to change. Do not change your doses or medication schedule without advice from your doctor.Do not stop taking selegiline suddenly or you may have harmful side effects. For best results, keep taking the medicine as prescribed. Store this medicine at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?Seek emergency medical attention if you think you have used too much of this medicine.
Symptoms of a selegiline overdose may include severe headache, hallucinations, vision problems, sweating, cool or clammy skin, fast or uneven heart rate, feeling light-headed, fainting, or seizure (convulsions).
What should I avoid while using selegiline?You must NOT eat foods that are high in tyramine, including:
Eating tyramine while you are taking selegiline can raise your blood pressure to dangerous levels which could cause life-threatening side effects.
You should become very familiar with the list of foods to avoid while you are taking selegiline.Avoid drinking alcohol while taking selegiline. Selegiline can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Selegiline side effectsGet emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking selegiline and call your doctor at once if you have any of these serious side effects:
Continue taking selegiline and talk with your doctor if you have any of these less serious side effects:
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What other drugs will affect selegiline?
Before taking selegiline, tell your doctor if you are using any of the following drugs:
If you are using any of these drugs, you may not be able to take selegiline, or you may need dosage adjustments or special tests during treatment.
There are many other medicines that can cause serious medical problems if you take them together with selegiline. Do not take selegiline before telling your doctor about all other prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Keep a list with you of all the medicines you use and show this list to any doctor, dentist, or other healthcare provider who treats you.
Where can I get more information?
What does my medication look like?
Selegiline is available with a prescription under the brand names Eldepryl and Zelapar. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.
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